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Similar to the majority of chronic diseases (for instance, diabetes), there is no cure for opioid use disorder, or any other addiction

Microneedling enhances drug delivery in three ways simultaneously, per the StatPearls dermatology reference and the Coelho 2022 review

Sun N, Liang Y, Chen Y, Wang L, Li D, Liang Z, et al

Enhanced Cellular Protection Protects against damage to cell membranes and supports immune response, acting as a natural defense against aging and environmental stress

After 30 minutes of incubation at 37 C in the dark, the percentage of PI positive cells was determined by using a flow cytometer (BD FACSCanto II, BD Biosciences), with 488 nm excitation laser and 585/42 nm band pass filter